Prospective Cohort Study of the Effectiveness of Smoking Cessation Treatments Used in the “Real World”

NOT Vape-related

To estimate the “real-world” effectiveness of commonly used aids to smoking cessation in England by using longitudinal data.

Published: October 2014

Positive: N/A

Link to publication: http://www.mayoclinicproceedings.org/article/S0025-6196(14)00629-6/fulltext

Authors

Daniel Kotz, PhD
Jamie Brown, PhD
Robert West, PhD


Summary

Patients and Methods

We conducted a prospective cohort study in 1560 adult smokers who participated in an English national household survey in the period from November 2006 to March 2012, responded to a 6-month follow-up survey, and made at least 1 quit attempt between the 2 measurements. The quitting method was classified as follows: (1) prescription medication (nicotine replacement therapy [NRT], bupropion, or varenicline) in combination with specialist behavioral support delivered by a National Health Service Stop Smoking Service; (2) prescription medication with brief advice; (3) NRT bought over the counter; (4) none of these. The primary outcome measure was self-reported abstinence up to the time of the 6-month follow-up survey, adjusted for key potential confounders including cigarette dependence.

Results

Compared with smokers using none of the cessation aids, the adjusted odds of remaining abstinent up to the time of the 6-month follow-up survey were 2.58 (95% CI, 1.48-4.52) times higher in users of prescription medication in combination with specialist behavioral support and 1.55 (95% CI, 1.11-2.16) times higher in users of prescription medication with brief advice. The use of NRT bought over the counter was associated with a lower odds of abstinence (odds ratio, 0.68; 95% CI, 0.49-0.94).


Conclusions

Prescription medication offered with specialist behavioral support and that offered with minimal behavioral support are successful methods of stopping cigarette smoking in England.

Full text in pdf format: Prospective Cohort Study of the Effectiveness of Smoking Cessation Treatments Used in the “Real World” – Mayo Clinic Proceedings